Blood Pressure Medicines May Raise Depression Risk – Says Study

Are you taking medicines for blood pressure? Be aware as it may enhance your mood disorder risk.

blood-pressureAccording to a recent study, people who are taking medicines to treat high blood pressure are more likely to feel depressed.

Dr. Sandosh Padmanabhan, professor at University of Glasgow in Britain said, “Mental health is under-recognised in hypertension clinical practice, and the possible impact of antihypertensive drugs on mental health is an area that physicians should be aware of and consider if the treatment of high blood pressure is having a negative impact on their patient’s mental health.”

To find out the association between high blood pressure medicines and mood disorders, the team of researchers examined the data of 144,066 hospitalized patients, aged between 40-80 years, taking different drugs including beta-blockers, angiotensin antagonists, calcium antagonist, and thiazide diuretics for at least 90 days to control their blood pressure.

These patients were compared to 111,936 other patients who were not taking any medication for blood pressure.

During the period of five years, total 299 patients were hospitalized for the mood disorder.

The study disclosed that people, who are taking beta-blockers and calcium antagonists for more than 90 days, were 2 times more likely to be hospitalized for major depression or bipolar disease than those taking so-called angiotensin antagonists for treating their high blood pressure.

Patients on angiotensin antagonists were at lower risk of developing mood disorders compared to those taking blood pressure medicines. Moreover, people taking thiazide diuretics are equally at risk of developing mood disorders as when compared to people taking no antihypertensive drugs.

Dr. Mann Fares, who is a cardiologist at the Cleveland Clinic in Ohio, agreed that people should not change their medication on the basis of this study. He was not involved in the study.

“It’s based on a retrospective analysis and the evidence isn’t sufficient to make any changes in our treatment patterns today,” said Fares.

He further added that the study, however, confirms the need for improved designed trials.

Professor Padmanabhan also warned that the study results are limited and he along with his team are currently observing some former clinical trials of blood pressure medicines to find out if those researchers had captured any information on depression, as it will make it easier to authorize the findings.

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